Collateral Damage

ADRs, ME/CFS, GWVs, Infections, MCS, metabollic syndromes and other "Syndromes"

It is no coincidence that many suffering ADRs are labeled as suffering from ME/CFS.

The mechanism leading to long term illness, stemming from ADRs, vaccines and the aforementioned, triggers glycation, inflammation, oxidative stress, producing too much Nitric Oxide and other free radicals, leading to degeneration over a long period of time, spanning between ten to twenty years.

Dis-Ease state manifests over a period of time, affecting the individual with a myriad of symptoms. Symptoms vary, but the mechanism is the same - TOXICITY. The mechanism begins with oxidization of endothelial cells leading to apoptosis (programmed cell death).

The general consensus amongst progressive medical doctors and scientists is that TOXICITY or nutritional imbalances are main causes of degenerative diseases.

It has already been established that medication causes damage to the mitochondria, leading to progressive degeneration manifesting as diabetes, and other auto-immune illnesses, metabolic syndromes, (http://aac.asm.org/cgi/reprint/AAC.00729-05v1.pdf and http://www.ceri.com/mito.htm) such as depleting L-Carnitine http://www.ncbi.nlm.nih.gov/sites/entrez and http://ods.od.nih.gov/factsheets/carnitine.asp, antibiotics weakening the immune system, activating viruses such as EBV and HHV-6. L-Carnitine deficiency is very difficult to diagnose, can lead to dangerous arrythmia and heart failure!

Furthermore, the principle that drugs only benefit a small percentage of the population as in this article: http://jcp.sagepub.com/cgi/content/abstr....ourcetype=HWCIT and hundreds more published articles, taking medicines is not only redundant, but will cause more harm.

Antibioitics can activate EBV & HHV6: http://tinyurl.com/yetmly3 and C.Difficile: http://tinyurl.com/ykqauw4

Likewise, antimicrobials are no longer effective, mutating pathogens, whilst weakening the immune system whilst causing even more damage to the digestive tract, which is 80% responsible for a healthy immune system!

Reading about oxidative stress, Nitric Oxide Cycle, Free Radicals, Inflammation over a period of two years, leads to the conclusion that preventing escalation of symptoms from ADRs is crucial to maintain good health.

Lastly, it is irrelevant if ME/CFS was triggered by an infection, which could have been triggered by the effects of antibiotics, or toxicity form vaccines, or medications. It will lead to oxidization and inflammation.

See articles below:

Treatment of myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS), a multisystem disease, should target the pathophysiological aberrations (inflammatory and oxidative and nitrosative stress pathways), not the psychosocial "barriers" for a new equilibrium.

Maes M, Twisk FN.

Patient Educ Couns. 2010 Mar 17. [Epub ahead of print]
Maes Clinics, Belgium.

In a recent article published by B. van Houdenhove and P. Luyten it is claimed that cognitive behavioral therapy and graded exercise therapy (CBT/GET) are evidence based and are the most adequate treatments to control symptoms and improve quality of life of patients with myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS). However, these authors do not disclose that their own treatments at the Belgian CFS Reference Centers with CBT/GET have proven to have no clinical effects. The Belgian minister declared in the parliament that CBT/GET at those centers are no curative therapies. Even more, measured by objective standards the CBT/GET approach has shown to be counterproductive. van Houdenhove and Luyten neglect or deny all scientific findings on the pathophysiology and possible medical treatments of ME/CFS. However, there is now a consensus that inflammatory and oxidative and nitrosative (IO&NS) pathways underpin the pathophysiology of ME/CFS in humans and in animal models as well. Human and animal data show that treatments which target IO&NS pathways are useful in treating ME/CFS. van Houdenhove and Luyten also propose that the time has come to shift treatment research in CFS from efficacy studies to effectiveness studies in 'real life'. In our opinion, future research should use a high throughput screening, made possible by the translational approach, in order to further examine the IO&NS pathways in detail; further delineate novel drug-targets in the IO&NS pathways and develop new drugs to treat this complex and serious medical disorder.

Medication-induced mitochondrial damage and disease.
Neustadt J, Pieczenik SR.
Montana Integrative Medicine, Bozeman, MT 59718, USA. drneustadt@gmail.com

Since the first mitochondrial dysfunction was described in the 1960s, the medicine has advanced in its understanding the role mitochondria play in health and disease. Damage to mitochondria is now understood to play a role in the pathogenesis of a wide range of seemingly unrelated disorders such as schizophrenia, bipolar disease, dementia, Alzheimer's disease, epilepsy, migraine headaches, strokes, neuropathic pain, Parkinson's disease, ataxia, transient ischemic attack, cardiomyopathy, coronary artery disease, chronic fatigue syndrome, fibromyalgia, retinitis pigmentosa, diabetes, hepatitis C, and primary biliary cirrhosis.

Medications have now emerged as a major cause of mitochondrial damage, which may explain many adverse effects. All classes of psychotropic drugs have been documented to damage mitochondria, as have stain medications, analgesics such as acetaminophen, and many others.

While targeted nutrient therapies using antioxidants or their precursors (e. g., N-acetylcysteine) hold promise for improving mitochondrial function, there are large gaps in our knowledge. The most rational approach is to understand the mechanisms underlying mitochondrial damage for specific medications and attempt to counteract their deleterious effects with nutritional therapies.

This article reviews our basic understanding of how mitochondria function and how medications damage mitochondria to create their occasionally fatal adverse effects.

In conclusion, staying from medication and finding the key to restoring health post ADRs is crucial. Doctors who risk their careers to expose this genocide should be taken seriously!!



Toxic Injury

According to toxicologists, varied and multiple toxicity symptoms will manifest from identical mechanism that is oxidization of endothelial cells.

Worth noting, the medical establishment is very quick at making judgments concerning toxicology of herbal remedies, but reluctant, even defiant about known adverse drug reactions (ADRS) and side effects ...

To recapitulate concerning the toxicology of Lariam/Mefloquine or other meds:

In general, pharmacologist accept that approximately, only 10% of meds are effective. Genetic variations, polymorphisms, biochemistry, ethnicity, weight, age, gender, body temperature, weather, etc ... all contribute to pharmacodynamics and pharmacokinetics. To date, it has not been possible to manufacture meds tailored for individuals precisely, because, there are so much that we don't know happening at cellular level.

The question here is why some don't react, rather, than, why we reacted? After all, Lariam/Mefloquine is toxic, as are fluoroquinolones and most meds.

The general consensus is that drug metabolism is unpredictable. http://tinyurl.com/yc6empe

DRUG METABOLISM/TRANSPORT

Nuclear Receptors and the Regulation of Drug-Metabolizing Enzymes and Drug Transporters: Implications for Interindividual Variability in Response to Drugs

Bradley L. Urquhart, PhD, Rommel G. Tirona, PhD and Richard B. Kim, MD

From the Division of Clinical Pharmacology, Department of Medicine (Dr Urquhart, Dr Tirona, Dr Kim), and the Department of Physiology & Pharmacology (Dr Tirona), University of Western Ontario, London, Ontario, Canada.

Division of Clinical Pharmacology, London Health Sciences Centre-University Hospital, Room ALL-152, 339 Windermere Road, London, Ontario N6A 5A5, Canada.

Erratic or unpredictable response to drugs remains a challenge of modern drug therapy. An important determinant of such interindividual differences in drug response is variability in the expression of drug-metabolizing enzymes and/or transporters at sites of absorption and/or tissue distribution. Variable drug-metabolizing enzyme and transporter expression can result in unpredictable exposure and tissue distribution of drugs and may manifest as adverse effects or therapeutic failure. In the past decade, important new insights have been made relating to the regulatory mechanisms governing the expression of drug-metabolizing enzymes and transporters by ligand-activated nuclear receptors. Specifically, there is compelling evidence to demonstrate that PXR, CAR, FXR, LXR, VDR, HNF4alpha, and AhR form a battery of nuclear receptors that regulate the expression of many important drug-metabolizing enzyme and transporters. In this review, the authors focus on clinically important drug-metabolizing enzymes such as CYP3A4, CYP2B6, CYP2C9, CYP2C19, UGT1A1, SULT2A1, and glutathione S-transferases and their regulation by nuclear receptors. They also review the nuclear receptor-mediated regulation of drug transporters such as MDR1, MRP2, MRP4, BSEP, BCRP, NTCP, OATP1B3, and OATP1A2. Finally, they outline how the drug development process has been affected by the current understanding of the involvement of nuclear receptors in the regulation of drug disposition genes.

Watch and learn, btw, good musik, by ES Prometheus - Enjoy

Since the Vids kept altering in the Video Bar,
those important vids concerning meds are now
embeded here instead:

Glutathione - brief review

Reading assiduously about raising glutathione leads me to conclude that the safest option is by taking its precursors such as Black Seed Oil, which apparently, can raise Glutathione by 800% , or Rosemary Edible OIl by 400% together with Vitamins C, E, Selenium, Zinc, and riboflavins.

Black seed oil has properties which are also anti-mutagenic, immune enhancer, anti fungal, and is even being studied for reversing cancer, chemopreventive and more.

It scavenges Nitric Oxide, decreases cholesterol, and blood lipid peroxide, has anti-inflammatory properties on vascular cells, induces leukemia cell apoptosis, and chemo preventive amongst other benefits.

See 3272 studies on PubMed: http://www.ncbi.nlm.nih.gov/sites/entrez

and here: http://www.lef.org/prod_hp/abstracts/php-ab469.html

Rosemary Edible Oil is not to be taken long term. It is very potent and a powrerful antioxidant being fat soluble, it helps detoxify the brain, helping the central nervous system. It also holds anti-cancerous compounds. It is excellent for cognition, helps boosting memory, cognition, oxygenate blood flow to the brain.

In addition, it has antiviral properties, helps restore liver function from toxic chemicals.

Studies show it stimulates bile function leading to the liver getting rid of chemical toxins. Note that bile plays an important role in nutrition.

Rosemary is also effective for digestive issues, is an immune modulator, and known to help with brain circulation.

It is also effective as an analgesic and arthritis.

Moreover, it is anti-mutagenic, and will help fight toxic chemicals restoring gene function!! It can be used against radiation as when exposed to scans, ionic x-rays etc..

See 874 studies on PubMed: http://www.ncbi.nlm.nih.gov/sites/entrez

Milk thistle if tolerated can stimulate the liver to rasie glutathione, but should not be taken for longer than two weeks, then stop the Milk thistle, and start again. It not a viable option, and may even cause toxicity in the long term.

Mmm, rambling thoughts, some waffling, venting and ruffling feathers .. about the obscenity that is Big Pharma!!! Its absurd and grotestque.

Medications do not save lives and do not cure. It is a belief system based on flagrant lies and skewed research, in most instances.

Studies show that during World I & World War II wounded soldiers, lived longer, without all the modern high tech modalities than do soldiers hospitalized during the last thirty years. Emergency surgery can save life, but then side effects from anesthetics, analgesics, antibiotics, may cause illness later on.

In addition, studies show that 6 out of 10 deaths in hospitals are attributed to medications. (posted on the forum from medical journal).

All meds and vaccines affect the mitochondria leading to more disease state, eventually.

Those who keep taking Fqs and say they are fine, they will develop some type of illness and will not even make the correlation.

This process differs from ADRs or suffering from side effects. The end result is that it can kill, maim, cause slow disease process spanning over many years, leading to a poor quality of life.

A healthy diet, stress reduction, exercise, good nutrition, regular gentle detoxing, avoidance of environmental pollution, keeping away from dentists and doctors, keeping well INFORMED, will keep disease at bay. Vigilance and health conscious. Early signs of disease process can be treated and in most cases reversed.

When we do hear of people who have reversed their late stage cancers, condemned by oncologists, or those who were cured of "cystic fibrosis" or Parkinson, or regained their sights, why do most people choose to either ignore this or simply choose not to believe? Why the skepticism?

Why the lack of respect for those very doctors who are speaking out against Allopathic Medicine, loosing their jobs, reputation, and career in the process? Instead, they are stripped of their medical license to practice and rejected both by their peers and the very people they seek to protect!!

Why not take heed? Why are they almost ridiculed? Why would more MDs speak out if they are not being supported by us?

Ghost writers, falsified drug trials results, publishers colluding by conjuring out of thin air medical journals (Elsvier), excluding those suffering ADRs in Phase I during drug trial, paying large sum of money to psychiatrist to endorse dangerous ineffective psychotropics, and to scientists and doctors in regards to poorly designed stents, DSM-IV growing lists of "mental" disorders (shyness now called social anxiety etc..), WHO Executive Board Members are totally corrupt - affiliated with PharmaCorps, unrestrained, altered the definition of "pandemic" in order to sell dangerous untested vaccines, based on poor science, for PROFIT. Widespread corruption involving agronomy, politicians, The list is long ...

Why does the mass choose to believe the Establishment?

Whenever I am at a Hospital talking to patients, they proudly hold on to their box full of pills, whilst relaying information about their failing healths, side effects and long list of diseases caused by their meds. Some of them suffered ADRs but continue to ignore obvoius connection.. Instead, they rush around seeing more doctors, given new labels, and more pills,

These patients end up in a cesspool of symptoms, feeling even more ill. Dying of a slow painful death over a period of ten to twenty years, with poor quality of life, munching away those very pills that are killing them slowly.

Why do they bury their heads in the sand, hoping for a cure, whilst health degenerating further.

I met a man with diabetes Type II. He was talking about insulin, and I was talking about throwing it away, altering his diet, taking vits and supps. Thanks to his "life saving insulin" he had a heart attack, followed by valve dysfuntion, ulcers on his legs, chronic vertigo, and multitude incapacitating symptoms. Is his diabetes controlled or cured? NO, instead, he is now taking more pills, deteriorating. I doubt he will live beyond the age of 45.

Studies have shown that those who take anti arrythmic are more likely die of sudden cardiac death, than those who don't.

Recently, published - Aspirin is NOT effective as a blood thinner and is no longer recommended. Ha, but, BUT, it will be useful for something else. New research shows that taking Aspirin reduces the chances of developing breast cancer, the list goes on.

Allopathic medicine is not an option. There are other therapeutic modalities, less toxic, less invasive worth exploring. So called "Alternative Medicine" should be regulated, open to scrutiny, and validation.

Having spent the last two years or so reading up medical journals, it is apparent, that ALL meds cause damage to the mitochondria, regardless, of side effects of those unfortunate suffering ADRs. (see Mitochondria dysunction caused by meds published articles and FDA threads).

All meds will cause damage leading to diabetes, auto immune illnesses, malfunction of the immune systems, metabolic syndromes (for which there are no labels yet), cardiac dysfunction, organ failure, neurological and degenerative illnesses and more.

Unlike those who suffer from ADRs, disease state will take a few years to develop. The connection is rarely made.

A new paradigm is emerging in allopathic medicine, that is cellular medicine, and Epigenetics of vitamins, supplements and various compounds from fruits, vegetables, herbs etc... Phytochemistry is more or less the same.

Is it new? NO, it is 4000 years old and been practiced by Ayurvedic doctors and Chinese doctors successfully, if the disease is caught early, the patient is willing to make life style changes, including breathing exercises.

No longer angry, replaced by sadness. I see the children of my friends born, beautiful, healthy. A few years later, post vaccines, struggling with asthma, allergies, moody, over active, infections and autoimmune illnesses etc ..

Enough waffling for now!!

I stumbled upon this article (below) today, and thought, it might be of interest.

"Jail Time for Executives Might Stop Drug Crimes" -
BusinessWeek
FYI
http://www.ahrp.org

"When Drug Makers' Profits Outweigh Penalties" appearing in today's Washington Post is an updated version of David Evans' riveting, prize winning investigative report, Big Pharma's Crime Spree, published in Bloomberg News, December 2009. Some of the tables from the expanded Bloomberg Magazine version can be accessed here, Big Pharma's Crime Spree. One thing remains unchanged:

"Across the United States, pharmaceutical companies have pleaded guilty to criminal charges or paid penalties in civil cases when the Justice Department finds that they deceptively marketed drugs for unapproved uses, putting millions of people at risk of chest infections, heart attacks, suicidal impulses or death."

The biggest fine ever imposed in U.S. history, $2.3 billion against recidivist Pfizer, represented a mere 14% of the revenue stream from selling the drugs at issue over seven years.

"So immune to criminal sanctions was that the company launched its off-label Bextra campaign at the same time the company was pleading guilty to doing precisely the same thing with other drugs. The anti-inflammatory medication was later yanked from the market because of increased risk of heart attacks and stroke."

Rather than being tried for their crimes rogue corporate giants in the pharmaceutical industry is being subsidized and the financial industr (giants deemed "too big to fail")-is being bailed out by US taxpayers.

A follow-up on Evans' report, Bloomberg News columnist, Ann Woolner took the bull by the horns in her column, "Jail Time for Executives Might Stop Drug Crimes" published by BusinessWeek (below) noting that: "Pharmaceutical and medical device companies repeatedly signal they just don't seem to care what the law says if they can find a way around it."

For example, "internal documents show Johnson & Johnson planning a push for $302 million in geriatric sales for a drug after the FDA had said that for the elderly, the medication wasn't as helpful and carried more risks than the company had claimed.The company denies wrongdoing."

"Throwing a few company executives in jail might do the trick."

The problem is the difficulty in proving intent. However, the Food and Drug Act, allows misdemeanor convictions without proof of intent to do wrongdoing. But until now, the FDA did not prosecute pharmaceutical executives.

So, the very rogue pharmaceutical companies that have pled guilty to criminal marketing of toxic, mostly useless drugs who paid hundreds of millions-even over a billion dollars in fines-have continued to profiteer from defective hazardous products.

Unless the FDA enforces the prosecutorial provisions of the FDC; unless Congress supports health-care fraud prosecutions; and unless the Obama administration will prohibit taxpayer reimbursement for criminally marketed
drugs and medical devices, rogue companies will continue profit from harm producing, hazardous drugs that pose risks of disability and death.

UK Persecution of ME/CFS sufferers, GWVs, ADRs, and victims of Iatrogenic illnesses

Many who suffer ADRs from meds, vaccines, environmental and iatrogenic illnesses are relentlessly persecuted in the UK. Most are given a diagnosis of ME/CFS - lack of both medical and social care, often leading to tragedy.

It should be simple to show toxicity from most drugs. Tests of DNA adducts would show traces of the offending medication, tissue samples, toe nail clippings, or even a hair sample, would probably show traces of the offending toxic medication. Yet, it is impossible to find a laboratory to test for residues of Lariam/Mefloquine or Fluoroquinolones in tissue samples.

The story of Sophie Mirza, diagnosed with ME/CFS is very significant. Many of us are diagnosed with ME/CFS. Sophie Mirza died after relentless persecution from UK health officials. Many are threatened by psychiatrists, psychologists of being sectioned. Medieval and cruel, it does not stop there. Sophie Mirza may unknowingly have suffered from an ADR to medication or vaccines.

Those chronically ill, specially those labelled with ME/CFS, are ground to a pulp by social security, social services, lack of medical care, denial by health professionals. This leads to fear, stress, and worsening of health. UK medical doctors no longer provide sick notes, clinical reports are misleading, omitting disabling symptoms, concealing positive results or blatant denial about the level of disability.

The welfare system and disability premiums are the lowest amongst the EU richest countries. It is barely sufficient and does not cover electricity, gas and other utilitiy bills. (Highest costs in the Western world, there is no regulatory price control). We have the highest rate of cold related deaths in the Western world!! The choice is between eat or heat, poor diet, leading to malnutrition makes it unlikely to recover from illness. Some countries in the EU cite the UK as the country where most chronically ill patients are unlikely to recover, (very low standard of socialized medicine) sinking even into deeper poverty (lowest social security amongst EU richest countries), and high cost of living.

Who would want to pretend to be ill under such draconian welfare system? Yet, many are "accused" of deception.

Despite being very weak and disabled, many are forced into physio leading to relapses and even more serious health issues.

As from October 2010, the criteria for being qualified as too ill to work will be very stringent, making most chronically ill patients "fit for work."

Unless paralyzed from head to toes, it will be very difficult to prove being too ill for work. The incentive is to force cheap labor for those too ill to work. If unable to go to work, we are told, work will come to you. Not accepting offer of work, will result in benefits being cut. Doctors no longer write sick notes. Clinic letters from hospital doctors are economical with diagnosis. It is a fight with clinicians, social services, and welfare. We are told, we have to "earn" welfare and disability. If forced to work from home, it will be equivalent to being paid $1 per hour.

Recently published in local regional newspapers, a man found dead in his apartment. He was unable to feed himself, social services refused care. Similarly, a woman was found dead on the floor of her kitchen. She was also refused care by social services.

A woman with a brain tumor was forced to work or face withdrawals of her welfare. She collapsed and could not continue to work.

A woman in her sixties, diagnosed with two cancers, underwent chemotherapy. Despite severe symptoms, doctors told her she was fit to work.

A man with cancer was told he had six months to live. He was told he had to work, and did not qualify for welfare.

Who would choose to be sick and ground to a pulp by a relentless pressure and a society increasingly hostile towards those who are ill - too ill to be productive? Who would choose to barely survive on minimum welfare and threats of dying of cold related illness during cold months?

Campaigners are muzzled, there is little free speech, the press is censored. Oh, and there is NO legal recourse. The UK opted out of the EU Social Charter.

Letters have been sent to Neurologists requesting that patients whose tests are negative, should be referred to a psychiatrist. Now, most of these tests are flawed. For instance, Mitochondrial diagnosis is very difficult to diagnose, tests are not specific with very low accuracy. There are metabollic syndromes caused by medications and vaccines, and environmental pollution, which are not identifiable, for which there are no tests.

Moving on to more persecution.


The told dying daugher she was lying, says mother Criona Wilson

Steve Bird

Recommend? (27)

Criona Wilson with a picture of Sophia, who died of ME aged 32

As Criona Wilson knelt beside her dying daughter’s bedside, she promised her that her death would not be in vain. Before the frail body of 32-year-old Sophia finally succumbed to the medical complications and ravages of ME, she replied in a whisper: “Then it’s all worth it.”

In the years that followed, Mrs Wilson, 66, a former midwife, dedicated her life to proving that her daughter’s condition was not a figment of imagination, nor one that merited her youngest child’s incarceration in a mental hospital.

Her battle saw her take on the medical profession and accepted thinking about the diagnosis and treatment of ME, also known as chronic fatigue syndrome. Eventually, in 2006, a coroner ruled that Sophia’s death was the result of myalgic encephalomyelitis — the first such ruling at an English inquest.

The fierce debate over ME has been highlighted once again by the case of Kay Gilderdale, who admitted assisting her daughter, Lynn, to kill herself after suffering from ME for 17 years. When she walked free from Lewes Crown Court on Monday, having been cleared of murder, Mrs Wilson was among those cheering her from the public gallery.

Related Links

• No blood test to diagnose if a patient has ME

• DPP defends murder charge against ME mother

“I had to be there,” said Mrs Wilson yesterday. “It was such an important case. And the verdict was a vote for common sense in a trial that highlighted what people suffering ME and their carers have to face.”

Her daughter, Sophia Mirza, was a talented and popular arts graduate living with her mother in Brighton in 1999 when she contracted ME at the age of 25. She became confined to her bedroom and, just as Miss Gilderdale had, needed round-the-clock care.

In 2003 she was visited by a psychiatrist, even though Miss Mirza complained only of physical discomfort. The psychiatrist told her that she was making up her symptoms and if she continued to pretend to be ill he would section her under the Mental Health Act. Mrs Wilson said: “I knew my daughter. There was no way she was mentally ill or pretending.”

When the dread knock on her door finally came in 2003, there was little she could do. A policeman forced the door open and the psychiatrist and a social worker locked themselves into Miss Mirza’s room to prepare her for her trip to a psychiatric ward.

Her condition took a dramatic turn for the worse. After 13 days she was released and taken back to the care of her mother. “That spell in a mental hospital set her back terribly. We lost all faith in medical professionals. We were alone,” said Mrs Wilson.

In 2005 Miss Mirza could barely muster the energy to speak, eat or drink. She and her mother had already agreed that no doctors should be called in case she would be sectioned again. On November 25, 2005, Miss Mirza died in her bed at home.

Wiping tears from her eyes, Mrs Wilson said: “We did everything we could.” Determined to get to the bottom of why her daughter’s treatment had been so bad, she got hold of her medical records. After being contacted by the 25 Per Cent ME Group, which campaigns for those with the most acute form of ME, she agreed to her daughter’s body being examined.

At the inquest the next year a neuropathologist told the court that Miss Mirza’s spinal cord was inflamed and three quarters of her sensory cells had abnormalities. It was, the court heard, a clear physical manifestation of ME. The coroner ruled that she had died from “acute renal failures as a result of chronic fatigue syndrome”.

A year later, the National Institute of Clinical Excellence (NICE) issued its first guidelines on the diagnosis and treatment of the illness, describing it as “relatively common”, affecting up to 193,000 people in Britain. At the heart of that guidance is the need to take into account the opinions of the patients.Mrs Wilson is campaigning to get the Government to fund research into ME. “It’s not over yet.

http://www.timesonline.co.uk/tol/life_and_style/health/article7008987.ece


This week, a mother was acquitted of murder. The question here is not about assisted suicide, but how could the so called fourth richest country in the world, allow ME/CFS patients be persecuted with such vehemence, and ignored by all?


Trapped by ME, Lyn Gilderdale made it clear she wanted to die

Lynn Gilderdale, who was struck down by ME after a BCG vaccination at the age of 14. Photograph: Sussex Police/PA

Live Journal was the one place where Lynn Gilderdale felt safe uttering her deepest, most troubling thoughts. Using a ­specially-designed handheld ­computer, and ­adopting the pseudonym Jessie Oliver, it was on the internet networking forum that she shared her desire to die with her closest friends.

After suffering a severe form of ME which left her bedridden and unable to speak or feed herself for all of her adolescent and adult life, she had decided she was never going to recover, and wanted to ensure her life would end before total degeneration robbed her of all dignity.

The revelations about her decision were made to her parents, Kay and Richard, and her small group of friends in the last two years of her life. To those who were invited to share her innermost thoughts it was a painful, yet understandable, choice.

Many of them were girls and young women who suffered the same illness; some, such as Lynn, had been confined to their beds and housebound for years as a result of ME.

"She did mention to me and very few others that she had an overwhelming desire to die," said Emily Levick. "I recall the time I first read about it. I cried, and then immediately texted her, as she was so afraid that her friends would think badly of her for it, and I wanted to reassure her that I could never think badly of her.

"She had battled for so many years, and was so desperately tired. It was quite literally heart breaking to read something like that, but I did understand her reasons. I believe I would have felt exactly the same if I were in her situation."

Her mother and father were kept well informed of her decision. A Do Not Resuscitate note was placed on her ­medical notes under her own wishes and she later went a step further and directed that a "living will" should be drafted in which she stated her wish not to be resuscitated or subjected to any medical intervention if her quality of life was too poor.

"She knew it was very difficult to talk to me about that subject because no one wants to hear it coming from their ­daughter," said Richard Gilderdale, a former policeman.

"I always used to say to her I was a coward because I listened to what she said and then she would always look at me with a knowing look in her eyes and say, 'Look, it's never going to go away, dad.' Her feelings were that she had made up her own mind that she couldn't carry on."

Yet despite this clear statement of her intentions, and fresh guidelines from the director of public prosecutions to reassure relatives who help the terminally ill end their own lives, Kay Gilderdale was brought before the criminal courts this month charged with the attempted ­murder of her 31-year-old child.

After she was acquitted of attempted murder today amid applause in court, the trial judge joined campaigners, friends and lawyers to ask why was she ever prosecuted? http://www.guardian.co.uk/society/2010/jan/25/lynn-gilderdale-me-assisted-suicide

The decision and responsibility to take Glutathione ultimately lies with you. Clear analysis and critical thinking is of value when deciding which approach to take.

There are contradictions about the use of Glutathione, whilst, many alternative doctors are using this frequently as an adjunct therapy, be aware of the risks. Few alternative doctors are putting the patient first. Most are not up to date with the research, not treating the patient as individuals, using therapies in many instances that are unsuitable.

Early on, I chose to take ImmunoPro - undenatured when protein, containing amino acids and bonded ceystine. Another product which has excellent endorsement from the medical community is called "Immunocal." Many I know reacted to this. It is recommended to start with a tiny quantity and increase over a period fo time. According to a well known CFS doctor, ImmunoPro works well and is gentler than Immunocal. Milk thistle and various other compounds are known to raise Glutathione.

It can be bought in capsules forms, (liposomal), sublingual, spray, transdermal patches, cream or IV.

I didn't think, based on my research, that it was safe to boost Glutathione level, for me, unless done over a period of time. If the digestive system, liver and kidneys are not functioning optimally, in particular Liver Detox Pathway I & II, it made no sense to raise Glutathione, rather than working as an antioxidant, it was likely it would turn into an oxidant and cause even more free radical damage.

It can also be harmful to those on Anti-depressants or with severe CNS symptoms. Again, do your research, be cautious.

Some foods that are known to raise Glutathione: broccoli, cabbage, avocado, artichokes, brussel spouts.

The simplest and easiest read about Glutathione below:

RAISING GSH LEVELS

If glutathione is manufactured within the body, what can we do to maintain or increase GSH levels? Some pharmaceutical drugs can do it, and so can some natural sources. Eating glutathione cannot. There are many ideas about how to raise GSH levels in the body but only a few actually work – and some of them have side effects. In order to take advantage of the great potential of GSH in health and disease we must dispel the myths and clarify the facts. This requires an understanding of the biochemical makeup of this important protein.

GSH is a tripeptide – a protein made up of three amino acids – in this case, glycine, glutamate (glutamic acid), and cysteine. The chemical structure of glutathione does not easily survive the digestive process, so eating it will not raise GSH levels. The body manufactures it within the cell from building blocks (precursors) of GSH in our food. Glycine and glutamate are readily available in North American diets, but cysteine-containing proteins are much harder to come by. Figure 12 shows sources of these three component amino-acids of glutathione.

Cysteine – a sulfur-containing, or "thiol" amino acid – is responsible for the biological activity (bioactivity) of the whole molecule. Cysteine as an isolated amino acid has trouble getting from your mouth to your cells. Much of it is broken down or altered in the digestive tract and bloodstream. So we must take cysteine in a form that resists breakdown. If the body doesn’t get these sulfur-containing amino acids into the blood, we can’t make GSH.

Other thiol amino acids include cystine (different from cysteine) and methionine. Cystine is known as a "disulfide" amino acid because it contains two cysteine molecules connected by their sulfur atoms – a so-called dilsulfide bridge. Cystine is not generally found as a free amino acid. Methionine may serve as a glutathione building block, but it has the tendency to convert into homocysteine, which raises the risk of heart disease.

There are several ways to raise GSH levels. Both pharmaceutical and natural products are listed in figure 13 and described in this chapter. We also describe how GSH as a whole works with other nutrients or co-factors.

Cont/... http://www.msmusings.com/archive81/FYI,%20raising%20glutathione%20levels.htm

What is Glutathione, why is it an intergral part of Recovery?

Simplified summary:

Glutathione is a major antioxidant, fighting disease process, by reducing free radicals activity. Many suffering physiological trauma such as from Vaccines, ADRs from medications, in particular CNS symptoms from neurotoxicity, ensuing disease process, either environmental or iatrogenic, resulting in oxidative stress, have very low Glutathione or dysfunctional GTSM1 Glutathione Transferase CYP Enzyme.

The mechanism involving Reactive Oxygen Species (ROS) plays a very important role in cell metabolism, cell signalling, BUT, if there is accumulation of free radicals, as well as dysfunctional detoxification Pathway I and Pathway II in the liver, it may result in cell death, and ensuing disease process over the years.

Nitric Oxide, (NO) a free radical, if allowed to accumulate, also contributes to disease process over a period of time, including, worsening of symptoms from neurotoxicity.

NO plays a major role in neurotoxicity, as well as the immune system, and physiology/biochemistry.

Scientists over the years, have focused on devising protocols to help lowering cell death from a rise in NO, and ROS. The general consensus is that there is if ROS is not kept under control, cell death and mutation will lead to inflammatory process and disease state.

Raising Glutathione and taking antioxidants are crucial in assisting recovery from ADRs.

Those undergoing chemotherapy in Germany, are also administered Glutathione IV, to avoid toxicity. If unable to tolerate Glutathione IV, other protocols such as N-acetylcysteine (NAC), a precursor of GSH, Alpha-Lipoic Acid (ALA), Vitamin C, Selenium, and Zinc, are gentler options.

NAC is often administered in hospitals to those suffering from dysfunctional/failing kidneys prior to contrast dye and other radioactive compounds to avoid toxicity.

The next post will include more information on Glutathione, AntiOxidants, gentle detox protocols, and the role of prevention through managing ROS and other Free Radicals.

Some research below, concerning the above.

http://www.ncbi.nlm.nih.gov/pubmed/19662025?ordinalpos=55&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
or
http://tinyurl.com/ygglddw

http://www.ncbi.nlm.nih.gov/pubmed/19715735?ordinalpos=13&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
or
http://tinyurl.com/yktxlkl

http://www.ncbi.nlm.nih.gov/pubmed/16444668?ordinalpos=23&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
or

http://tinyurl.com/yf6rhwe


http://www.ncbi.nlm.nih.gov/pubmed/19782114?ordinalpos=13&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
or
http://tinyurl.com/yzdpodz


http://www.ncbi.nlm.nih.gov/pubmed/19689380?ordinalpos=49&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
or
http://tinyurl.com/yjpo8r8

What is Glutathione by Dr Mark Hyman

Detoxing, gently, safely!!

Ill for 13 years post ADRs, It is only last year, that I have been able to start (with great difficulties) on a protocol for methylation, mitochondria (diagnosed with mitochondrial dysfunction), detoxing, diet and nutrition. Progress is hampered by severe allergies, MCS, and severe CYPs (enzymes in the digestive system, kidneys, liver and brain, all connected) dysfunction.

It is not possible, to swallow a whole vitamin, even at the lowest dosage, unless trying tiny crumbs from each, tablet, lasting several days/weeks, building up to tolerance level.

I am very restricted in what I can take concerning vits and supps. However, raising the glutathione by taking its precursors, and attempting to take anti-oxidants, is yielding results in some areas.

There is some improvement in some areas, whilst not in vascular, cardiac, liver function and severe weakness. Difficult to quantify, at this time.

Those I personally know who applied themselves to raising glutathione, tajung anti-oxidants, some gently, over a period of time, some more aggressively by taking NAC, ALA, selenium and Vit C, others doing Glutathione IV, have all benefited, without side effects.

Some have reacted to Glutathione IV, depending their own health status, and medications, sensitivities, and allergies.

"The Detox System: Detoxification of Biotoxins in Chronic Neurotoxic Syndromes"

By John Foster, M.D., Patricia Kane, Ph.D., Neal Speight, M.D.

Chronically ill individuals suffering from neurotoxin exposure impacts patient populations with CFIDS, Fibromyalgia, MS, Autism, Cardiovascular Disease, Depression, Rheumatoid Arthritis, IBS, Infertility, ALS, Parkinsons, Lyme, Toxic Building Syndrome, Estuary Associated Syndrome, Psychosis, Diabetes without family Hx, Optic Neuritis, Refractory Heavy Metal Toxicity, Pulmonary Hemorrhage, Stroke. Patients diagnosed with these chronic illnesses may be potentially classified as 'Neurotoxic Membrane Syndrome' (NMS) with the endothelial cell membrane as the target of degeneration.


While hypercoagulation involves a myriad of proteins, it is ultimately a membrane event, essentially disrupting the phospholipids that structure the membrane. Agglomeration (blocked cellular exposure to blood flow/nutrients and impaired cell-to-cell communication) indicates elevation of phospholipase A2 and the uncoupling of eicosanoids from the cell membrane causing inflammation. The agglomeration that eventually occurs is, in essence, a product of a weakened membrane, and ultimately a disturbed red cell fatty acid profile.


Clinical Research

We have established a biomedical protocol in our clinics, The Haverford Wellness Center in Havertown, PA and The Center for Wellness in Charlotte, NC for patients with neurotoxic illness. Our biomedical approach is an attempt to reach the systemic nature of these tenacious neurotoxic syndromes and provide clinically proven methods that eradicate neurotoxins. Our course of action is that of freeing the patient of pervasive symptoms of neurotoxic illness in a noninvasive manner that heals the membrane, and ultimately the body and brain.

The recent pioneering work of Ritchie Shoemaker, M.D., as communicated in his book Desperation Medicine and his peer reviewed papers (Shoemaker 2001), lends strong support to a connection between Chronic Fatigue Syndrome, Fibromyalgia, Lyme Disease, Pfiesteria infection and that of numerous Neurotoxic Syndromes.

Biotoxins as Neurotoxins

The presentation of biotoxin exposure often parallels neurological and psychological impairment due to the interrelationship between the ENS (Enteral Nervous System) and the CNS. The biliary tree, gall bladder, and bile formation within the liver serve in the vital processes of detoxication (disposal of waste products bilirubin, heavy metals, biotoxins, xenobiotics), lipid metabolism, transport and digestion (bile acids). Abnormalities of the hepatobiliary system may involve biliary stasis whereby infectious material or biotoxins reside within the liver, biliary tree and gall bladder, as a viscous suspension in biliary sludge.

Biotoxins as bacteria, viruses, parasites, spirochetes, dinoflagelletes, and fungus may be within biliary sludge often creating neurotoxins impacting the CNS via the ENS, or the Second Brain (gut). The occurrence of biliary sludge may be due to prolonged fasting, low fat intake, high carbohydrate diets or exposure to pathogens. Restriction of dietary fat may impair biliary flow which would be contraindicated in attempting to clear toxicity as bile is paramount to cleansing the body and getting biotoxins and heavy metals excreted into the fecal matter.

Neurotoxins are minute compounds between 200-1000 KD (kilodaltons) that are comprised of oxygen, nitrogen and sulfate atoms arranged in such a way as to make the outside of the molecule fat loving and water hating. As such, once it enters the body, it tends to bind to structures that are rich in fat such as most of our cells, especially the liver, kidney, and brain. Neurotoxins are capable of dissolving in fatty tissue and moving through it, crossing cell membranes (transporting against a gradient, particularly with potassium) disrupting the electrical balance of the cell itself.

As fat soluble neurotoxins move through the cells of the body from the GI tract to sinus to lung to eye to muscle, to joint to nerve, whereby they eventually enter the liver and the bile. Once neurotoxins bind with bile they have access to the liver, the body is poisoned over and over again as the bile is re-circulated (first released into the intestine to digest fats, and then reabsorbed).

Neurotoxins cause damage by disrupting sodium and calcium channel receptors, attacking enzyme reactions involved in glucose production thereby disrupting energy metabolism in the cell, manufacturing renegade fatty acids as saturated very long chain, odd chain and branched chain fatty acids impairing membrane function, stimulating enzymes (PLA2) which uncouple essential fatty acids from the cell membrane and impairing the function of the nuclear receptor PPAR gamma which partially controls transcription (the conversion of instructions held in our DNA to RNA which then leads to translation or protein production in the cell).

Heavy Metals reside in Fatty Tissue with Biotoxins

Heavy metals are also lipid soluble and often compound the removal of biotoxins (Aschner et al 1990, 1998; Dutzak 1991). As has been observed by many clinicians, often as the patients' heavy metal toxicity is addressed they are faced with the additional complication of the presence of biotoxins. Biotoxins and heavy metal exposure co-exist within the cell membrane and fatty tissue requiring consideration for both types of toxicity in regard to patient intervention.

By stabilizing glutathione we in turn impact metallothionein markers (Nordberb and Nordberb 2000, Ebadi et al 1995, Sato et al 1995, Kerper et al 1996, Susanto et al 1998), glycoaminoglycans or GAGS (Klein 1992), methylation, sulfation, hepatic and renal function as we introduce treatment protocols for detoxication with gentle, natural modalities that unload cellular toxicity safely. GSH infusion by fast IV push has been a remarkable tool to unload the body burden of heavy metals and neurotoxins in both pediatric and adult populations, without side effects.

Cont/..
http://tinyurl.com/yql6ad

Navy Soldiers die after receiving Swine Flu Shot

(MY own personal view, is that, figures being published concerning deaths attributed to swine flu are highly questionable, according to polls, so does a high percentage of the population.

Few trust the reporting system, after all, we suffered serious life threatening ADRs from toxic medications, and vaccines, and still - being denied the toxicity diagnosis. How can any regulatory healthy institutions be trusted??


Courtesy of Bob Chapman of The International Forecaster

Subject: Vital data about US Navy results of swine flu vaccine on ship

Data gleaned indirectly from anonymous testimony of Navy wives of the affected crew via the internet radio show A Marine Disquisition http://www.clipser.com/watch_video/1362067 :

1. Unnamed US Navy vessel put to sea in April with 347 man crew.
2. Entire crew was vaccinated with H1N1 Swine Flu vaccine shortly after they put to sea.
3. Crew sickened so severely that other ships had to respond to render aid. 16 Medical Dr.s put aboard from an unnamed aircraft carrier and other responding vessels. Total of 50 Navy personnel sent aboard to respond to crisis.
4. Two of the crew of 347 died – including the Captain of the ship (a Lieutenant Commander) and a Chief Petty Officer.
5. 50 personnel sent aboard to help are quarantined in Navy hospital in Balboa, Spain after 10 of them caught the flu from the ship’s crew. Two of the 50 quarantined are in serious condition at last report.
6. Of the 347 man crew that were vaccinated, 333 contracted the H1N1 flu FROM THE VACCINE. Two died, as mentioned above, and 331 survived. Only 14 of the 347 vaccinated sailors did not show any ill effects from the vaccine.
7. Navy has threatened all the spouses of the ship’s crew to remain silent – claiming all this information is classified. Some are whistle-blowing and that is where this information is coming from.
8. On the unnamed aircraft carrier that provided assistance, 415 sailors contracted the swine flu and are currently quarantined onboard.

PLEASE pass this email along. The truth is that the swine flu epidemic will be created BY THE VACCINE. If we don’t take it, there will be no epidemic. From this one test it’s apparent that the vaccine as tested on that ship’s crew in April is 96% effective at infecting the recipient with swine flu. Such an infection rate is impossible to achieve by any natural means. Though it only killed 1% immediately, there is no telling what the long term effects on those injected with the vaccine will be. See the research on the long term effects of the 1976 swine flu vaccine, and the Gulf War anthrax vaccine programs for more information.

Also note that mere contact with those that have been vaccinated creates a 20% chance of you contracting the swine flu even if you have not been vaccinated.

Please pass this data along to anyone you care about!

http://www.cbsnews.com/stories/2009/07/21/health/main5177494.shtml
http://www.resistnet.com/profiles/blogs/navy-soldiers-are-dying-from

VIDEO: Navy Soldiers are dying from swine flu shot




CAPTAIN, CPO DEAD AFTER SWINE FLU SHOTS

	Re: Swine flu cover up « Reply #19 Today at 9:13am »
Navy Soldiers die after receiving Swine Flu Shot Official figures of deaths attributed to H1N1 swine flu, are highly questionable. My own personal belief, and that of many, find those figures unconvincing and propaganda. Likewise, deaths following swine flu shots are being kept under wraps!! There is no conflict of interest here, except exposing the truth. Courtesy of Bob Chapman of The International Forecaster Subject: Vital data about US Navy results of swine flu vaccine on ship Data gleaned indirectly from anonymous testimony of Navy wives of the affected crew via the internet radio show A Marine Disquisition http://www.clipser.com/watch_video/1362067 : 1. Unnamed US Navy vessel put to sea in April with 347 man crew. 2. Entire crew was vaccinated with H1N1 Swine Flu vaccine shortly after they put to sea. 3. Crew sickened so severely that other ships had to respond to render aid. 16 Medical Dr.s put aboard from an unnamed aircraft carrier and other responding vessels. Total of 50 Navy personnel sent aboard to respond to crisis. 4. Two of the crew of 347 died – including the Captain of the ship (a Lieutenant Commander) and a Chief Petty Officer. 5. 50 personnel sent aboard to help are quarantined in Navy hospital in Balboa, Spain after 10 of them caught the flu from the ship’s crew. Two of the 50 quarantined are in serious condition at last report. 6. Of the 347 man crew that were vaccinated, 333 contracted the H1N1 flu FROM THE VACCINE. Two died, as mentioned above, and 331 survived. Only 14 of the 347 vaccinated sailors did not show any ill effects from the vaccine. 7. Navy has threatened all the spouses of the ship’s crew to remain silent – claiming all this information is classified. Some are whistle-blowing and that is where this information is coming from. 8. On the unnamed aircraft carrier that provided assistance, 415 sailors contracted the swine flu and are currently quarantined onboard. PLEASE pass this email along. The truth is that the swine flu epidemic will be created BY THE VACCINE. If we don’t take it, there will be no epidemic. From this one test it’s apparent that the vaccine as tested on that ship’s crew in April is 96% effective at infecting the recipient with swine flu. Such an infection rate is impossible to achieve by any natural means. Though it only killed 1% immediately, there is no telling what the long term effects on those injected with the vaccine will be. See the research on the long term effects of the 1976 swine flu vaccine, and the Gulf War anthrax vaccine programs for more information. Also note that mere contact with those that have been vaccinated creates a 20% chance of you contracting the swine flu even if you have not been vaccinated. Please pass this data along to anyone you care about! http://www.cbsnews.com/stories/2009/07/21/health/main5177494.shtml http://www.resistnet.com/profiles/blogs/navy-soldiers-are-dying-from VIDEO: Navy Soldiers are dying from swine flu shot CAPTAIN, CPO DEAD AFTER SWINE FLU SHOTS http://www.cbsnews.com/stories/2009/07/21/health/main5177494.shtml http://www.resistnet.com/profiles/blogs/navy-soldiers-are-dying-from http://theplaintruth.websitetoolbox.com/post?id=3686614