Showing posts with label Nutrition Epigenetics - DNA altering compounds. Show all posts
Showing posts with label Nutrition Epigenetics - DNA altering compounds. Show all posts

Wednesday, November 24, 2010

Opponents of nutrition, epigenetics (vits & supps ability to switch on/off genes), herbal and indigenous medicine, herbal, phytochemistry, WATCH OUT...

The very medical journals promoting toxic meds, adhered to, in most instances, ineffective, are now investing billions in research (nothing new and done before) ;D promoting Vit D3, Fish Oil, and more.

Previously dismissive of research and studies by independent institutions, they are now preparing for a take over vits and supps etc... Every day, as if on cue, articles being published concerning therapeutic properties for these. [image]

The article below, is really nothing new!! Nutritionists have known for decades about nitrates contained in beet juice (and other fruits & vegs) promotes energy by less oxygen in take. It is claimed that athletes, those suffering from cardiovascular and respiratory diseases and the elderly would benefit.

Eating foods containing high content of nitrates, to increase endurance. NOT, cured bacon, ham, meats, hotdogs, INSTEAD, spinach, lettuce, and leafy vegetables.

Beetroot juice reduces high blood pressure too.

Those who continue to take toxic meds, do your home work, take a close look at compounds in those meds, and read up, simply does not make sense and does not cure!!

J Appl Physiol. 2009 Aug 6. [Epub ahead of print]
Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans.
Bailey SJ, Winyard P, Vanhatalo A, Blackwell JR, Dimenna FJ, Wilkerson DP, Tarr J, Benjamin N, Jones AM.

Exeter University.

Pharmacological sodium nitrate supplementation has been reported to reduce the O2 cost of sub-maximal exercise in humans. In this study, we hypothesised that dietary supplementation with inorganic nitrate in the form of beetroot juice (BR) would reduce the O2 cost of sub-maximal exercise and enhance the tolerance to high-intensity exercise. In a double-blind, placebo-controlled, crossover study, eight males (aged 19-38 yr) consumed 500 mL per day of either beetroot juice (BR, containing 11.2 +/- 0.6 mM of nitrate) or blackcurrant cordial (as a placebo, PL, with negligible nitrate content) for six consecutive days, and completed a series of 'step' moderate-intensity and severe-intensity exercise tests on the last 3 days. On days 4-6, plasma [nitrite] was significantly greater following dietary nitrate supplementation compared to placebo (BR: 273 +/- 44 vs. PL: 140 +/- 50 nM; P<0.05) and systolic blood pressure was significantly reduced (BR: 124 +/- 2 vs. PL: 132 +/- 5 mmHg; P<0.01). During moderate exercise, nitrate supplementation reduced muscle fractional O2 extraction (as estimated using near infra-red spectroscopy). The gain of the increase in pulmonary VO2 following the onset of moderate exercise was reduced by 19% in the BR condition (BR: 8.6 +/- 0.7 vs. PL: 10.8 +/- 1.6 mL(.)min(-1)(.)W(-1); P<0.05). During severe exercise, the VO2 slow component was reduced (BR: 0.57 +/- 0.20 vs. PL: 0.74 +/- 0.24 L.min(-1); P<0.05) and the time-to-exhaustion was extended (BR: 675 +/- 203 vs. PL: 583 +/- 145 s; P<0.05). The reduced O2 cost of exercise following increased dietary nitrate intake has important implications for our understanding of the factors which regulate mitochondrial respiration and muscle contractile energetics in humans. Key words: VO2 kinetics, exercise tolerance, exercise economy, slow component.

http://www.ncbi.nlm.nih.gov/pubmed/19661....Pubmed_RVDocSum
The role of Epigenetics, rather than DNA, is involved in disease process.
Moreover, it puts the emphasis on compounds in nutrients (eg foods) that is often a determinant factor. (See vid below)

Basically, Epigenetics is about altering cell function with without changing DNA sequencing, and this is achieved by altering diet rich in methyl donors. I am now making a U-Turn, ;) and will be going back to reading up again on Methylation.

There are tons of evidence to show that the Genomics can't be used to determine if one will develop a particular disease. Furthermore, it has failed miserably to design medications specific to Genomics. Add to that, that gene polymorphisms are often open to interpretation and stats.

This means that a gene polymorphism for one type of particular cancer, is also associated with other disease process, but through Epigenetics, in this case, nutrients, can alter the course of disease process (if not too advanced).

Medical doctors are not trained in this field. Nutritionist, biochemists, biomolecular and molecular biology are much more knowledgeable concerning Epigenetics.

That is what it means to me, to prepare the terrain, right at cellular activity. Anything else, IMHO, is superficial, and will not bring long term healing.

This is why I chose Ayurvedic Medicine, which can be compared to Phytochemistry, and closest to repairing to methylation and damaged DNA. In essence. It uses various compounds (60% from fruits) to alter the course of cellular activities. To research methylation and Epigenetics would be too absorbing and time consuming, Ayurvedic, for me, right now is a short cut.

Various acclaimed Institutions and Teaching Hospitals, Vitamins and Supplements, and Sports Companies, as well as a Swiss Pharmaceutical Company are using Ayurvedic Medicine, the latter patented an excellent compound for cardiac dysfunction. Ayurvedic use different terminology, but overall, it is far more than just being a monotherapy. It works on all systems and functions in the body, applying diet and nutrition, psychology, meditation, breathing, spirituality etc..

Ayurvedic Medicine is becoming Westernized, and are slowly selling out. It is leading to being trivialized and corrupted.

Inevitably, this leads to a schism between purists and westernized Ayurvedic Practitoners. But then again, Western Science and Allopathic Medicine is not without polemics.

Professor Jeremy Nicolson has been working on metabolomics since 1980s and other scientists. Concluded was that there are far more metabolism variation than genetic variations.

From MIT:
About the Lecture
Forget cigarette smoking (well, not completely). The really bad news, says Leona Samson, is that by virtue of the act of living, a human body will be exposed to destructive threats from the environment, and from within itself. Charbroiled burgers, sunlight, pollution, and even how our bodies use oxygen all pose what Samson calls “insults” to the DNA of our cells.

Our success in fending off these inevitable DNA-damaging agents in the environment depends a lot on inheritance, Samson tells us. For instance, victims of the rare disease Xeroderma pigmentosum don’t have the capacity to repair DNA that’s been corrupted by UV radiation from the sun. Children with Xeroderma pigmentosum develop skin cancers. In the larger population, such cancers tend to occur much later in life. The reason, Samson says, is that most of us have a formidable array of mechanisms within our cells for detecting and mending defective DNA. Cells with flawed DNA that goes unrepaired must either die, or go on to mutate in often dangerous ways.

Samson wants to figure out how to protect cells against carcinogenic effects in the environment, and whether a tumor cell will be susceptible to treatment. She has been painstakingly studying the Saccharomyces cerevisiae yeast organism, trying to identify all the factors that determine whether or not DNA damaging agents kill or mutate cells. She interrogated each of this organism’s 5,800 genes, “asking one by one, which of you is making a product that’s important to helping a cell recover from damage.” In what was a “huge surprise,” Samson learned that there are more than 2,000 gene products involved in helping a yeast cell repair itself, “from areas of the cell never suspected before for being important” in this way. Now Samson must elucidate the complex cellular pathways that “talk to each other” when DNA is damaged -- and figure out “how to extend to humans, ultimately.”


Kiwis could protect DNA from damage, says pilot study

By Stephen Daniells, 26-Jul-2006

Related topics: Science & Nutrition, Fruit, vegetable, nut ingredients

Two to three kiwis a day could keep cancer at bay by helping to repair damaged DNA, suggests a pilot study from the home of the fruit.

A pilot study from New Zealand has reported that a daily "prescribed" kiwifruit, in tandem with dietary advice and improved physical activity, led to a significant increase in repair of damaged DNA.

""Prescription" of daily kiwifruit may provide a sustainable population intervention that could reduce some of the risk factors associated with cancer," wrote lead author Elaine Rush from AUT University in Auckland.

Studies from the same university have reported that kiwifruit have laxative effects and could help combat serious cases of constipation, while studies from the University of Oslo have reported that two to three kiwifruit a day significantly reduced blood clotting in human volunteers and could offer protection from strokes and deep vein thrombosis.

The new randomised controlled trial recruited 12 healthy volunteers (six men, six women, average age 43, average BMI 27.5 kg per sq. m). For the first three weeks the subjects were left to live 'normally' with no dietary intervention. After week 3, all subjects were given lifestyle advice, including eating habits and physical activity.

After week 6, the subjects were randomly assigned to either the control (no kiwifruit) group, or to receive a daily dose of kiwifruit equivalent to one kiwi for every 30 kg of body weight.

Blood samples were taken at the start and at subsequent three week intervals to measure blood lipid levels (cholesterol, triglycerides) and to assess DNA damage markers.

No significant changes were observed for weight, blood pressure, or blood cholesterol and triglyceride levels for either of the groups.

This last result is at odds with the Oslo research that reported a drop of 15 per cent for triglyceride levels, although the intervention times are not the same, which limits the ability to directly compare.

http://www.foodnavigator.com/Science-Nutrition/Kiwis-could-protect-DNA-from-damage-says-pilot-study
Extract from article:

"Think you’re being healthy by choosing a veggie burger instead of red meat? Think again.

...In an effort to make their products as low-fat as possible, many veggie burger manufacturers are turning to a potentially harmful chemical, according to an investigation by the non-profit Cornucopia Institute. It revealed in a recent report that most non-organic veggie burger brands contain a chemical called hexane, which is an EPA-registered air pollutant and neurotoxin.

This lovely chemical is traditionally reserved for shoe glue, leather products and roofing. ...
...So, they soak soybeans in hexane so they can separate the fat from the protein.

According to the Cornucopia Institute’s report, “if a non-organic product contains a soy protein isolate, soy protein concentrate, or texturized vegetable protein, you can be pretty sure it was made using soy beans that were made with hexane.”
...The Cornucopia Institute also revealed some popular veggie burger brands that absolutely do use hexane: Amy’s Kitchen, Boca Burger, Franklin Farms, Garden Burger, It’s All Good, Lightlife, Morningstar Farms, President’s Choice, Soy Boy, Taste Above, Trader Joe’s and Yves Veggie Cuisine.

Brands that do not use any hexane in their veggie burgers are: Helen’s Kitchen, Superburgers by Turtle Island, Tofurky, Wildwood and Morningstar “Made with organic”...+Sunshine Burger"

http://yourorganicgardeningblog.com/health-warningneurotoxin-in-veggie-burgers/
Black Rice Is Cheap Way to Get Antioxidants

Authors and Disclosures

Information from Industry

Bacterial RTIs: Consider the importance of broad-spectrum coverage See coverage in community-acquired pneumonia (CAP) Read more

August 27, 2010 — Inexpensive black rice contains health-promoting anthocyanin antioxidants, similar to those found in blackberries and blueberries, new research from Louisiana State University indicates.

"Just a spoonful of black rice bran contains more health promoting anthocyanin antioxidants than are found in a spoonful or blueberries, but with less sugar and more fiber and vitamin E antioxidants," Zhimin Xu, PhD, of Louisiana State University Agricultural Center, says in a news release. "If berries are used to boost health, why not black rice and black rice bran?"

Xu and colleagues analyzed samples of black rice bran from rice grown in the Southern U.S.

He says black rice bran would be a unique and inexpensive way to increase people's intake of antioxidants, which promote health.

Black rice is rich in anthocyanin antioxidants, substances that show promise for fighting cancer, heart disease, and other health problems, Xu says.

He adds that food manufacturers could use black rice bran or bran extracts to boost the health value of breakfast cereals, beverages, cakes, cookies, and other foods.

Black Rice vs. Brown Rice

The most widely produced rice worldwide is brown. Millers of rice remove the chaff, or outer husks, from each grain to make it brown.

White rice is made when rice is milled more than is done for brown rice; the bran is also removed, Xu says.

The bran of brown rice contains high levels of one of the vitamin E compounds known as "gamma-tocotrienol" as well as "gamma-oryzanol" antioxidants.

Many studies have shown that these antioxidants can reduce blood levels of LDL "bad" cholesterol and may fight heart disease.

So black rice bran may be even healthier than brown rice, Xu says.

He and his colleagues also showed that pigments in black rice bran extracts can produce a variety of colors, from pink to black, and may be a healthier alternative to artificial food colorants that manufacturers now add to some foods and beverages.

He writes that several studies have linked some artificial colorants to cancer, behavioral problems in children, and other adverse health effects.

Currently, black rice is used mainly in Asia for food decoration, noodles, sushi, and pudding, and Xu says that he would like to see it eaten by more Americans.

Black rice bran could be used to boost the health value of foods, such as snacks, cakes, and breakfast cereals, Xu and his colleagues suggest.

This study was presented at a medical conference in Boston. The findings should be considered preliminary because they have not yet undergone the "peer review" process, in which outside experts scrutinize the data prior to publication in a medical journal.
Walnuts, walnut oil, improve reaction to stress
October 4, 2010

A diet rich in walnuts and walnut oil may prepare the body to deal better with stress, according to a team of Penn State researchers who looked at how these foods, which contain polyunsaturated fats, influence blood pressure at rest and under stress.

Previous studies have shown that omega-3 fatty acids -- like the alpha linolenic acid found in walnuts and flax seeds -- can reduce low density lipoproteins (LDL) -- bad cholesterol. These foods may also reduce c-reactive protein and other markers of inflammation.

"People who show an exaggerated biological response to stress are at higher risk of heart disease," said Sheila G. West, associate professor of biobehavioral health. "We wanted to find out if omega 3-fatty acids from plant sources would blunt cardiovascular responses to stress."

The researchers studied 22 healthy adults with elevated LDL cholesterol. All meals and snacks were provided during three diet periods of six weeks each.

The researchers found that including walnuts and walnut oil in the diet lowered both resting blood pressure and blood pressure responses to stress in the laboratory. Participants gave a speech or immersed their foot in cold water as a stressor. Adding flax seed oil to the walnut diet did not further lower blood pressure. They report their findings in the current issue of the Journal of the American College of Nutrition.

"This is the first study to show that walnuts and walnut oil reduce blood pressure during stress," said West. "This is important because we can't avoid all of the stressors in our daily lives. This study shows that a dietary change could help our bodies better respond to stress."

A subset of the participants also underwent a vascular ultrasound in order to measure artery dilation. Results showed that adding flax oil to the walnut diet significantly improved this test of vascular health. The flax plus walnuts diet also lowered c-reactive protein, indicating an anti-inflammatory effect. According to West, that could also reduce risk

http://www.physorg.com/news205387690.html

Sunday, May 16, 2010

Professor Yiannis Samaras and Dr Effimia Eriotou found Thyme Essential Oil, (as in herb thyme) and Cinnamon Essential Oil are effective against MRSA!! It was suggested that these could be used as food preservatives instead of toxic chems. Known for thousands of years, validated in 2010!! http://tinyurl.com/ydopvre

Yummy.


See also the post on Black Seed Oil, which is under Glutathione Label

List of some Fluoroquinolones Antibiotics

List of some fluoroquinolones antibiotics- for list of symptoms go to: www.fluoroquinolones.org
forum: www.favc.info


Generic & Brand Name of most common Fluoroquinolones

Brand Name: Trovan - Zithromax
Generic Name: Trovafloxacin and Azithromycin

Brand Name: Factive
Generic Name: Gemifloxacin Mesylate

Brand Name: Zagam
Generic Name: Sparfloxacin

Brand Name: Vigamox
Generic Name: Moxifloxacin

Brand Name: Vigamox
Generic Name: Moxifloxacin

Brand Name: Cinobac
Generic Name: Cinoxacin

Brand Name: Penetrex
Generic Name: Enoxacin

Brand Name: Tequin
Generic Name: Gatifloxacin (Removed from US Market - May 2006)

Brand Name: Levaquin
Generic Name: Levofloxacin

Brand Name: Floxin
Generic Name: Ofloxacin

Brand Name: Synercid
Generic Name: Quinupristin and Dalfopristin

Brand Name: Trovan - Zithromax

Brand Name: Zymar
Generic Name: Gatifloxacin Ophthalmic Solution

Brand Name: Avelox
Generic Name: Moxifloxacin HCL

Brand Name: Floxin Otic Singles

Brand Name: Ciprodex
Generic Name: Ciprofloxacin and Dexamethasone

Brand Name: Raxar
Generic Name: Grepafloxacin

Brand Name: Ocuflox
Generic Name: Ofloxacin Ophthalmic

Brand Name: Quixin
Generic Name: Levofloxacin

Brand Name: Cipro
Generic Name: Ciprofloxacin

Brand Name: Proquin XR
Generic Name: Ciprofloxacin Hcl

Brand Name: Requip XL
Generic Name: Ropinirole Extended Release Tablets

Brand Name: Zanaflex
Generic Name: Tizanidine

Brand Name: Noroxin
Generic Name: Norfloxacin

Brand Name: Maxaquin
Generic Name: Lomefloxacin Hcl

Brand Name: Ciloxan Ophthalmic Solution
Generic Name: Ciprofloxacin HCL Ophthalmic Solution

Brand Name: Cipro XR
Generic Name: Ciprofloxacin Extended-Release

Generic Name Norloaxin Brand Name: Noroxin

Generic Name Temafloxacin Brand name Omniflox