Lariam side effects

Through legistlation in 2002, Roche included side effects and adverse reactions to Lariam/Mefloquine for patients inserts. The Department of Veterans also published a list of side effects causing long term damage. This includes, cardiovascular, gastrointestinal, endocrinological, cognitive, neuropsychiatric, sensory system, haematological, kidneys, liver, skin, neurological, mitochondria, ions channels, showing how toxic this chemoprophylaxis can be! Connecting the dots with ChemoProphylaxis??

Note that on all inserts in packaging, side effects are described as "Rare" or "Infrequent" does not reflect some published articles, or what is being reported. More on FDA's and MRHA's reporting system later.

Unfortunately, many symptoms are delayed and can manifest themselves sometimes two or more years after taking it.

Furthermore, taking one pill only, can and do cause listed above damage to many. Medical Doctors are very reluctant to give a diagnosis of Lariam toxicity, making it very difficult for patients to access care, except for psychotropics, if suffering from neuropsychiatric symptoms. These drugs are not helpful long term, are addictive and cause more damage to neuronal circuitry. Overall, Medical Doctors, rarely, if ever, diagnose prescribed drug Adverse Reactions. They are dismissive of correlation of symptoms and side effects!!

Factors involved in side effects and adverse reactions are poorly understood. Extraneous variables include what was eaten on that day, alcohol consumption, the temperature, gender, ethnicity, weight, CPYs in the liver, digestive system, kidneys, detoxification Phase I & Phase II, genetic polymorphisms, and pharmacodynamics/pharmacokinetics of Lariam. In no way, does this mean that there is a genetic malfunction, rather, that Lariam is a very toxic drug, and those who do not react are very lucky. This could be due to the fact that during that period of time, they were able to avoid Lariam reaching toxic level by excreting it more efficiently. It is worth noting that most drugs are only effective for less than 10% fo the general population.

It is not feasible to manufacure any pharmaceutical drugs to suit everybody's unique biochemistry.

Published research focuses on neuropsychiatric and neurological side effects, in particular suicides, but lacking in other long term side effects such as cardiovascular, which can be devastating.

For those of you suffering from side effects from Lariam, please read:

http://tiny.cc/2rKP9
http://tiny.cc/oPnlZ
http://www.lariam.dk/Trial.htm

I have an old pdf format of a document concerning long terms effects of Lariam from the Department of Veterans Affairs, which was not found on their site today. Has it been deleted? Those who wish to have a copy, please register, leave a comment with your email address, requesitng your email address to be deleted before publishing your comments.

For those of you suffering neuropsychiatric symptoms, there is hope. These symptoms will fade in time, specially for those who are able to resist the lure of psychotropics. Do not allow psychiatrists convince you that you had an underlying psychiatric condition which suddenly appeared after taking Lariam. Or that you are personality Type A, driven and ambitious, thriving on stress, etc. Lariam does NOT work that way.

Some medications, in particular Lariam and Fluoroquinolones are known to cause chaos in neuronal circuitry. Moreover, there is little knowledge concerning neuronal circuitry, but sufficient data and research show serious damage to the central nervous system, can and do occur by certain types of medications.

The next post will focus on Lariam pharmacodynamics and pharmacokinetics.

Information and published papers concerning Lariam/Mefloquine were NOT copied from any other Lariam sites, but researched from the orignial source.